Recently Filed Direct Compression Patents

By: Pharma Tips | Views: 3302 | Date: 14-May-2011

Direct Compressible Excipients, which can be used universally with any of the APIs, can lead to a revolution in tablet manufacturing techniques by way of low cost and efficient tablet rnanufacturing. These economical advantages will be beneficial for both manufacturing and consumer, we can also go for certain synthetic but inert materials, and by using them we can produce tablets using ingredients than otherwise could not possibly be compressed to a tablet.


Direct Compressible Excipients, which can be used universally with any of the APIs, can lead to a revolution in tablet manufacturing techniques by way of low cost and efficient tablet rnanufacturing. These economical advantages will be beneficial for both manufacturing and consumer, we can also go for certain synthetic but inert materials, and by using them we can produce tablets using ingredients than otherwise could not possibly be compressed to a tablet. From all this, the direct compression technique can be taken as the best alternative for conventional tablet manufacturing and is best suited to industrial expectations too.

Nowadays, we have a long list of materials which can help in the direct compression of certain materials, which are otherwise not easy to be directly compressed, and this is done by imparting certain characteristics. To the materials to be compressed and by the use of certain new technologies, all together, these excipients can lead to easy manufacturing of tablet dosage forms for the APIs, which are not compatible with water, and thus make the use of the wet granulation technique difficult.

Table. Recently filed direct compression patents

Sr. no.

Us patent number

Objective/title

1

20020182259

Stanuforth, John N. et.al

Process for preparing a directly compressible solid dosage from containing MCC.

2

20040142059

Gereg. George. W.

Apparatus for predicting the suitability of substance for dry granulation by roller compaction using: small sample size.

3

Jasprova. Dagmar

tablet obtained by D.C compressing 4-amino- 1-hydroxy butylide-ne-1, 1-bis-phosphoric acid as active ingredient

4

20039161878

Durig, Thomas, et.al.  

Highly compressible Ethyl cellulose for tableting.

5

20030147949

Stanuforth, John N.et.al,

Pharmaceutical excipient having Improved Compressibility.

6

4159345

Takero.et.al

D.C-excipient consists essentially of MCC.

 

7

4744984

Mehra et al.

A particulate Co-Processed MCC & CaCo3  Composition (D.C Excipient)

8

E.P.4744987

Asahi Kabushiki Kaisha

D.C-Excipient containing Powdery MCC.

 

9

201120054903

Tyler, Joseph, Petersen, Johns

 

Compressed Tablet comprising of a compressed

Core comprised of at least 80% by weight of an aliphatic amine polymer.


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