Characterization of Nanosuspensions

By: Pharma Tips | Views: 4430 | Date: 02-Jun-2011

A critical parameter that defines the quality and physicochemical behavior ofnanosuspensions is the particle size distribution. The mean particle size and widthof distribution can be determined using photon correlation spectroscopy (PCS),laser diffraction (LD), and coulter counter techniques.

A critical parameter that defines the quality and physicochemical behavior of
nanosuspensions is the particle size distribution.

The mean particle size and width of distribution can be determined using photon correlation spectroscopy (PCS),
laser diffraction (LD), and coulter counter techniques.

The measuring range for PCS is 3 nm to 3 mm and LD can measure particles ranging from 0.05 to 80 mm
up to 2,000 mm.

The coulter counter gives an absolute number of particles per unit
volume for the different size classes.

The shape and surface morphology of nanosuspensions can be assessed by scanning electron microscopy and atomic force
microscopy.

The crystalline state of nanosuspensions can be characterized by differential
scanning calorimetry and X-ray diffraction.

Determination of zeta potential is important to assess the physical stability of nanosuspensions.

For nanosuspension formulations administered intravenously, additional parameters
such as surface hydrophilicity/hydrophobicity, sterility, and pyrogenicity need to
be determined.
Previous Page Next Page

People Searching On This Page:
  • nano suspension
  • characterization of nanosuspension
  • stability of nanosuspension
  • stability of nanosuspensions
  • nanosuspension microscopy
  • determination
  • characterisation of nano suspension
  • atomic force microscopy in nanosuspension
  • nanosuspension in bangladesh
  • characterisation of nanosuspension
  • Stability of Nanosuspensions
  • nano suspension in pharmaceutics
  • Critical size of an atomic particle

Related Pages


Applications of Nanosuspensions

Applications of Nanosuspensions

Articles | Pharmaceutics | Suspensions
Date:
02-Jun-2011  Views: 4791

Nanosuspension technology is applicable to all poorly soluble drugs and an outstandingfeature of this technology is its simplicity. ...
Preparation of NanoSuspensions

Preparation of NanoSuspensions

Articles | Pharmaceutics | Suspensions
Date:
02-Jun-2011  Views: 4703

Nanosuspensions can be produced by bottom-up or top-down techniques. In thecase of bottom-up technique, the strategy is to build particles from their ...
Introduction of Nanosuspensions

Introduction of Nanosuspensions

Articles | Pharmaceutics | Suspensions
Date:
02-Jun-2011  Views: 5548

Many of the marketed drugs and a large proportion (40%) of potentially bioactivemolecules from drug discovery are poorly soluble in aqueous and nonaqu ...
Characterization of MicroEmulsion

Characterization of MicroEmulsion

Articles | Pharmaceutics | Emulsions
Date:
02-Jun-2011  Views: 4931

Characterization of microemulsions is a difficult task because of the variety ofstructures and components involved, and the limitations with the avail ...
Characterization of Emulsion

Characterization of Emulsion

Articles | Pharmaceutics | Emulsions
Date:
02-Jun-2011  Views: 11440

The type of emulsion prepared can be determined by simple tests such as dilutiontest, dye solubility test, and electrical conductivity test. The dilut ...
Post Your Comments (No Login Require)
Name : (required)
Email : (required)
Website :

Comment : (required)

67  + 4 =     
Comments
People Searched About:
Nano Suspension   |   Characterization Of Nanosuspension   |   Stability Of Nanosuspension   |   Stability Of Nanosuspensions   |   Nanosuspension Microscopy   |   Determination   |   Characterisation Of Nano Suspension   |   Nano Suspension In Pharmaceutics   |   Critical Size Of An Atomic Particle   |  
Google : 780 times | Yahoo : 20 times | Bing : 259 times |