Dry Heat Sterilizer - Operation & Features

By: Pharma Tips | Views: 4156 | Date: 23-Feb-2012

The Dry Heat Sterilizer is used in Pharmaceuticals and Biotechnology for sterilization and depyrogenation of glassware, containers, vessels, machine and components.

Dry Heat Sterilizer
Introduction:
The Dry Heat Sterilizer is used in Pharmaceuticals and Biotechnology for sterilization and depyrogenation of glassware, containers, vessels, machine and components.

At MACHINFABRIK, with over 200 installations world-wide, we can offer you systems that comply with the most exacting international regulatory requirements for your critical process needs.

Our Dry Heat Sterilizers are available in two options - Class 100 and Class 10,000. We also give you a wide range of choices on the chamber capacity, loading configurations and process control and recording.

The DHS finds application for humidity sensitive materials such as glassware and metal containers that can be sterilized by steam sterilizers but cannot depyrogenate the load.

At MF, we assure the performance of DHS meeting the following specifications.

• STERILIZATION: Reduction of microbial spore forms up to 12 log reduction.

• DE-PYROGENATION: Denaturing of microbial endotoxins in the material.
 

Dry Heat Sterilizer


Technique:
The DHS operation is based on hot air recirculation technique.

The centrally placed load is subjected to hot air circulation by means of an impeller and heater bank arrangement.

Centrally placed impeller ensures circulation via heater bank spaced in the recirculation zone.

Clean air for recirculation is sucked via the Pressure module through a pre filter and high retention HEPA filter (99.997% efficiency)

The efficiency of DHS depends on the velocity and circulation pattern of air within the sterilization zone.



Features:
• The inner chamber is fabricated from S.S. 316 or S.S. 316L and is fully welded to ensure a crevice free and easy to clean environment.
• Compliance with USFDA,UKMCA norms.
• Temperature Uniformity +/- 5 degree Celsius guaranteed within the chamber for the entire cycle.
• STERILIZATION efficiency of 12 log reduction.
• HEPA filter of 99.97% performance for clean air.
• Extended shaft motor for chamber recirculation.
• Positive Pressure throughout the cycle for 100% Sterile integrity of the load.
• Automatic plc controlled cycle with user-friendly operator interface for visual monitor and control over the entire cycle.
• Blind Temperature Controller for overshoots temperature condition.
• From the point of view of chamber safety, the heater bank and fan motor are electrically interlocked.
• Door Interlocking to prevent simultaneous opening of both doors.
• Door Process lock to prevent opening of doors when process is on.
• "Sterile door lock" to prevent sterile door opening unless the sterilization cycle has been successfully completed.
• Circulation Blower or heater malfunction alarm.
• Automatic Fh Calculator with facility for control in case of heat labile materials.
• On-line printing [alpha-numeric and graphical ] for process documentation.


Applications:

• Glassware (Containers such as ampoules, vials etc.).
• Metal trays.
• Containers and metal material.
• Machine and accessories used in production.
• Various types of humidity sensitive material.


Optional Features:
Thyristor controlled operation : For efficient control of heater bank, thyristorised operation via PLC can be optionally provided giving an advantage of better temperature control and uniformity.

Class 100 DHS :
With a view to comply with the latest G.M.P. & U.S. FDA standards, we put to test the technical expertise of our dedicated engineers to successfully developed the CLASS-100 Sterilization Systems.

• High temperature HEPA filters (0.3 micron, performance 99.97%) are installed in the circulation loop to ensure Class-100 environment in the chamber.

• Differential pressure indicators for monitoring performance of HEPA filter bank.

• Improved filter seating arrangement for maximum filter surface.

• New baffle design for uniform airflow and temperature uniformity between the top-bottom and sides of the sterilization chamber.


Previous Page Next Page

People Searching On This Page:
  • nmt4
  • DHS chamber pressure
  • dhs pharma company use
  • dhs sterilization hepa filter dp
  • dhs sterilization
  • Dry Heat Sterilizer uses
  • depyrogenate
  • homemade dry heat sterilizer using plc
  • dhs for depyrogenate
  • limulus amebocyte lysate method/Procedure

Related Pages


Rapid Cooling Sterilizer - Operation & Features

Rapid Cooling Sterilizer - Operation & Features

Articles | Pharmaceutical Equipment | Injection
Date:
07-Mar-2012  Views: 5431

For terminal sterilization of specific products the conventional steam sterilization method is rendered ineffective as the load within an ampoule or a ...
HPHV Steam Sterilizer - Operation & Features

HPHV Steam Sterilizer - Operation & Features

Articles | Pharmaceutical Equipment | Injection
Date:
26-Feb-2012  Views: 12182

Today's pharmaceutical market demands exacting temperature/pressure control, process automation and system documentation.The Steam Sterilizer from Mac ...
Dry Syrup Filling and Sealing Machine

Dry Syrup Filling and Sealing Machine

Articles | Pharmaceutical Equipment | Injection
Date:
20-Nov-2011  Views: 5692

CLEANING PROCEDURE FOR DRY SYRUP FILLING AND SEALING MACHINE ...
Fluid Bed Dryer Operating Procedure

Fluid Bed Dryer Operating Procedure

Articles | Pharmaceutical Equipment | Tablet
Date:
02-Oct-2011  Views: 14568

Fluid bed dryer also named fluidized bed dryer is one of our main products. To know its working principle, first you should know what "fluidizd bed" i ...
Dry Granulation and Compression of Spray-Dried Plant Extracts

Dry Granulation and Compression of Spray-Dried Plant Extracts

Articles
Date:
18-Mar-2011  Views: 4533

The purpose of this research was to evaluate the influence of dry granulation parameters on granule and tablet properties of spray-dried extract (SDE) ...
Post Your Comments (No Login Require)
Name : (required)
Email : (required)
Website :

Comment : (required)

43  + 9 =     
Comments
People Searched About:
Nmt4   |   DHS Chamber Pressure   |   Dhs Pharma Company Use   |   Dhs Sterilization Hepa Filter Dp   |   Dhs Sterilization   |   Dry Heat Sterilizer Uses   |   Depyrogenate   |   Homemade Dry Heat Sterilizer Using Plc   |  
Google : 256 times | Yahoo : 13 times | Bing : 341 times |